Osteogenesis imperfecta: the role and place of orthopedic surgery of the lower extremities
https://doi.org/10.18019/1028-4427-2021-27-4-461-467
Abstract
Introduction. Surgical correction of orthopedic problems in children and adults with severe osteogenesis imperfecta is of interest to the medical community.
The aim of this study was to review the current relevant literature on the role of orthopedic surgery in the treatment of children and adults with osteogenesis imperfecta and the integration of surgery into a multidisciplinary approach to the treatment of patients with osteogenesis imperfecta. The review is based on the material of the report presented at the first educational conference of the European Pediatric Orthopedic Society which was held in Russia at the Ilizarov Center in 2021.
Material and methods. To prepare the review, we searched for information sources at the scientific platforms such as PubMed, Scopus, ResearchGate, RSCI, as well as published products (Elsevier, Springer).
Results and discussion. The review includes a discussion of the classification, indications, features of the surgical technique and the early postoperative period, the role of early functional loading, the features of long-term treatment results of using telescopic transphyseal constructs in the correction of deformities of lower limb long bones as well as issues of the combination of orthopedic surgery and bisphosphonate therapy.
Conclusion. Orthopedic support of children and adults with severe and moderate types of osteogenesis imperfecta requires construction of a multifactorial strategy that takes into account the requirements of physical therapy and medication treatment, as well as the use of specialized implants, instrumentation and methods of surgical intervention, while an optimal solution has been still sought.
About the Authors
D. A. PopkovRussian Federation
Dmitry A. Popkov, M.D., Ph.D., Professor of RAS, correspondent member French Academy of Medical Sciences,
Kurgan
E. R. Mingazov
Russian Federation
Eduard R. Mingazov, M.D.,
Kurgan
A. V. Gubin
Russian Federation
Alexander V. Gubin, M.D., Ph.D.,
Moscow
N. S. Gvozdev
Russian Federation
Nikita S. Gvozdev,
Kurgan
A. M. Aranovich
Russian Federation
Anna M. Aranovich, M.D., Ph.D., Professor,
Kurgan
A. L. Semyonov
Russian Federation
Alexander L. Semyonov,
Novosibirsk
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Review
For citations:
Popkov D.A., Mingazov E.R., Gubin A.V., Gvozdev N.S., Aranovich A.M., Semyonov A.L. Osteogenesis imperfecta: the role and place of orthopedic surgery of the lower extremities. Genij Ortopedii. 2021;27(4):461-467. https://doi.org/10.18019/1028-4427-2021-27-4-461-467