Comminuted tibial fracture healing by the use of the mineral complex Micellate (experimental study)

Abstract

Purpose Experimental study of the effect of Micellate on the processes of reparative regeneration on the model of comminuted tibial fractures. Materials and methods The paper analyzes the results of studies carried out on 20 mongrel dogs in whom comminuted tibial fractures were modeled. To stimulate osteogenesis, a complex of minerals called Micellate was used. Results It was found that Micellate acts selectively and restores the lack of the bone tissue mineral component. The regenerate remodels into an organotypic bone in a shorter time. Conclusion After a detailed study of the mechanisms of action and clinical trials, the preparation might find application both in the correction of osteopenia and osteoporosis that develop in the process of fracture consolidation, and for the prevention of fractures caused by the loss of the mineral component of bone tissue as a result of metabolic disturbances.