Structure and quantitative evaluation of bone density and bone mineral content in patients with vitamin D-resistant rickets and in those with vitamin D-deficient rickets consequences before treatment

Abstract

Computer tomography (CT) and densitometry (DXA) were used to study structure, density and mineral density (BMD) of lower limb bones in 32 patients with vitamin D-resistant rickets and in those with vitamin D-deficient rickets consequences. In patients with vitamin D-resistant rickets a roughly trabecular structure with trabeculae located in random way preponderated in epimetaphyseal bone parts, the least values of bone density were observed in femoral and tibial epiphyses (175 ± 85 HU and 174 ± 84 HU, respectively), there was bone age lagging behind the passport one, while in patients with vitamin D-deficient rickets consequences both epiphyses and metaphyses have fine cellular structure, zones of preliminary calcification are represented by isolated thin strips of sclerosis, bone age conforms to the passport one.