Results of a differentiated approach to open decompression of the median nerve in carpal tunnel syndrome
https://doi.org/10.18019/1028-4427-2026-32-2-172-185
Abstract
Introduction Open decompression of the median nerve is a common surgery performed for carpal tunnel syndrome (CTS). Transection of the transverse carpal ligament (TCL) results in impaired hand biomechanics and decreased grip strength when specific anatomy necessitate transection of the thenar muscles along with the ligament.
The objective was to compare short-term and long-term surgical results of CTS patients treated with open decompression in three different settings: without thenar muscle reconstruction, with thenar muscle reattachment and with reconstruction of the thenar muscles.
Material and methods A total of 80 patients with idiopathic CTS treated with 92 surgical procedures were included in the study. They were divided into three groups. The first group included 38 patients (39 surgeries) treated with open decompression without reconstruction of the TCL. Forty surgical procedures were produced for 31 patients of the second group including dissection and reattachment of the thenar muscles located at the site of the median nerve dissection. Median nerve decompression followed by TCL reconstruction were performed for 11 patients of the third group treated with 13 surgical procedures.
Results All patients demonstrated positive dynamics with more significant recovery of the hand function achieved after open decompression of the median nerve and reattachment of the thenar muscles and reconstruction of the spinal nerve with the outcome improved at three months and stabilized at six months of the surgery.
Discussion A differentiated approach to treatment ensured the amplitude of the M-response of the brevis muscle abducting the pollicis increased by 15.9 % in the first group, by 34.3 % in the second group, and by 30.5 % in the third group; the impulse velocity along the motor fibers of the median nerve increased by 6.6 %, 13.2 %, and 10.9 %, respectively, at six months. Less improvement in electrophysiological parameters in patients of the first group could be associated with a more advanced surgical technique employed for the patients of the second and third groups.
Conclusion A comparative analysis of the short-term and long-term surgical outcomes of CTS patients revealed clinically significant improvement with both options. However, the hand function recovery was more accomplished in the second and third groups with use of the two methods we developed.
About the Authors
S. N. IzmalkovRussian Federation
Sergey N. Izmalkov — Doctor of Medical Sciences, Professor, Head of the Department
Samara
O. M. Semenkin
Russian Federation
Oleg M. Semenkin — Candidate of Medical Sciences, orthopaedic surgeon, Associate Professor of the Department
Samara
A. N. Bratiychuk
Russian Federation
Alexander N. Bratiychuk — Doctor of Medical Sciences, Professor of the Department
Samara
A. K. Usov
Russian Federation
Alexey K. Usov — Candidate of Medical Sciences, Head of the Department, Associate Professor of the Department
Samara
N. A. Demchenko
Russian Federation
Nikita A. Demchenko — postgraduate student, orthopaedic surgeon
Samara
А. E. Guseva
Russian Federation
Alena Ev. Guseva —functional diagnostics doctor
Samara
K. F. Khairullina
Russian Federation
Kira F. Khairullina — ultrasound diagnostics doctor
Samara
References
1. Peshin SE, Karakulova YV, Nyashin YI, Nyashin MM. Carpal tunnel syndrome in terms of biomechanics. Literature review. Russian Journal of Biomechanics. 2022;26(2):13-18. (In Russ.) doi: 10.15593/RZhBiomeh/2022.2.01.
2. Fuss FK, Wagner TF. Biomechanical alterations in the carpal arch and hand muscles after carpal tunnel release: a further approach toward understanding the function of the flexor retinaculum and the cause of postoperative grip weakness. Clin Anat. 1996;9(2):100-108. doi: 10.1002/(SICI)1098-2353(1996)9:2<100::AID-CA2>3.0.CO;2-L.
3. Ludlow KS, Merla JL, Cox JA, Hurst LN. Pillar pain as a postoperative complication of carpal tunnel release: a review of the literature. J Hand Ther. 1997;10(4):277-282. doi: 10.1016/s0894-1130(97)80042-7.
4. Lluch A. Reconstruction of the flexor retinaculum. In: Luchetti, R., Amadio, P. (eds) Carpal Tunnel Syndrome. Springer, Berlin, Heidelberg.; 2002:226-238. doi: 10.1007/978-3-540-49008-1_32.
5. Mujadzic T, Friedman HI, Mujadzic MM, et al. Modified Carpal Tunnel Release: A New Approach to Minimizing Pillar Pain. Ann Plast Surg. 2021;86(6S Suppl 5):S503-S509. doi: 10.1097/SAP.0000000000002885.
6. Morán-Morán J, Mérida-Velasco JR, Del Valle EB, Murillo-González J. A mini-incision carpal tunnel release technique to prevent pillar pain: A technical note. Acta Orthop Traumatol Turc. 2021;55(1):73-75. doi: 10.5152/j.aott.2021.20086.
7. Castro-Menéndez M, Pagazaurtundúa-Gómez S, Pena-Paz S, et al. Z-Elongation of the transverse carpal ligament vs. complete resection for the treatment of carpal tunnel syndrome. Rev Esp Cir Ortop Traumatol. 2016;60(6):355-365. doi: 10.1016/j.recot.2016.06.007.
8. Alsafar F, Li ZM. Thenar and Hypothenar Muscle Coverage on the Transverse Carpal Ligament. J Wrist Surg. 2021;11(2):150-153. doi: 10.1055/s-0041-1735887.
9. Hollevoet N, Barbaix E, D’Herde K, et al. Muscle fibres crossing the line of incision used in carpal tunnel decompression. J Hand Surg Eur Vol. 2010;35(2):115-119. doi: 10.1177/1753193409102465.
10. Jegal M, Woo SJ, Lee HI, et al. Anatomical Relationships between Muscles Overlying Distal Transverse Carpal Ligament and Thenar Motor Branch of the Median Nerve. Clin Orthop Surg. 2018;10(1):89-93. doi: 10.4055/cios.2018.10.1.89.
11. Chern TC, Jou IM, Chen WC, et al. An ultrasonographic and anatomical study of carpal tunnel, with special emphasis on the safe zones in percutaneous release. J Hand Surg Eur Vol. 2009;34(1):66-71. doi: 10.1177/1753193408097322.
12. Izmalkov SN, Semenkin OM, Bratiichuk AN, Demchenko NA. Method for refixation of thumb thenar muscles in open median nerve decompression in patients with carpal tunnel syndrome. Patent RF, no. 2828980, 2024. Available at: https://www.fips.ru/registers-doc-view/fips_servlet?DB=RUPAT&DocNumber=2828980&TypeFile=html.. Accessed Feb 02, 2026. (In Russ.)
13. Kotelnikov GP, Lartsev YuV, Izmalkov SN, et al. Surgical method for patients with carpal tunnel syndrome. Patent RF, no. 2734176. 2020. Available at: https://www.fips.ru/registers-doc-view/fips_servlet?DB=RUPAT&DocNumber=2734176&TypeFile=html. Accessed Feb 02, 2026. (In Russ.)
14. Beck JD, Wingert NC, Rutter MR, et al. Clinical outcomes of endoscopic carpal tunnel release in patients 65 and over. J Hand Surg Am. 2013;38(8):1524-1529. doi: 10.1016/j.jhsa.2013.05.016.
15. Hudak PL, Amadio PC, Bombardier C. Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The Upper Extremity Collaborative Group (UECG). Am J Ind Med. 1996;29(6):602-608. doi: 10.1002/(SICI)1097-0274(199606)29:6<602::AID-AJIM4>3.0.CO;2-L.
16. Rozov AV, Lila AM, Byalik EI, et al. Results of tendon transfers for stabilization of wrist joints for patients with rheumatoid arthritis. Science and Innovations in Medicine. 2024;9(4):311-316. (In Russ.) doi: 10.35693/SIM633628.
17. Levine DW, Simmons BP, Koris MJ, et al. A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome. J Bone Joint Surg Am. 1993;75(11):1585-1592. doi: 10.2106/00004623199311000-00002.
18. Yusupova DG, Suponeva NA, Zimin AA, et al. Validation of the Boston Carpal Tunnel Questionnaire in Russia. Neuromuscular Diseases. 2018;8(1):38-45. (In Russ.) doi: 10.17650/2222-8721-2018-8-1-38-45.
19. Semenkin OM, Izmalkov SN, Bratiichuk AN, et al. Results of surgical treatment of patients with carpal tunnel syndrome depending on the severity of the disease. Genij Ortopedii. 2021;27(1):24-31. doi: 10.18019/1028-4427-2021-27-1-24-31.
20. Nikolaev SG. Electromyography: clinical practice. Ivanovo: PresSto; 2019:392. (In Russ.)
21. Gilveg AS, Parfenov VA, Evzikov GYu. Median nerve decompression in carpal tunnel syndrome: short- and long-term results. Neurology, neuropsychiatry, psychosomatics. 2018;10(3):79-85. (In Russ.) doi: 10.14412/2074-2711-2018-379-85.
22. Belyakov YV, Ivanenko AV, Oleynik EA, et al Complications of surgical treatment and relapses of carpal tunnel syndrome. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2021;13(4):15-21. (In Russ.)
23. Gartsman GM, Kovach JC, Crouch CC, et al. Carpal arch alteration after carpal tunnel release. J Hand Surg Am. 1986;11(3):372-374. doi: 10.1016/s0363-5023(86)80144-7.
24. Luchetti R, Amadio P. Carpal Tunnel Syndrome. Berlin: Springer; 2002:121-129. doi: 10.1007/978-3-540-49008-1.
25. Seitz WH, Lall A Open carpal tunnel release with median neurolysis and Z-plasty reconstruction of the transverse carpal ligament. Current Orthopaedic Practice. 2013;24(1):53-57. doi: 10.1097/BCO.0b013e3182797ac3.
26. Netscher D, Steadman AK, Thornby J, Cohen V. Temporal changes in grip and pinch strength after open carpal tunnel release and the effect of ligament reconstruction. J Hand Surg Am. 1998;23(1):48-54. doi: 10.1016/S03635023(98)80088-9.
27. Kotelnikov GР, Povelikhin AK, Knyazev NA, et al. Long-term results of surgical treatment with the use of transverse carpal ligament reconstruction in patients with carpal tunnel syndrome depending on the age categories and severity of the disease. Bulletin of the Medical Institute "REAVIZ". 2023;13(2):56-61. (In Russ.) doi: 10.20340/vmirvz.2023.2.CLIN.6.
28. Kumar AA, Lawson-Smith M. Pillar Pain After Minimally Invasive and Standard Open Carpal Tunnel Release: A Systematic Review and Meta-analysis. J Hand Surg Glob Online. 2024;6(2):212-221. doi: 10.1016/j.jhsg.2023.12.003.
29. Bernstein RA. Endoscopic carpal tunnel release. Conn Med. 1994;58(7):387-94.
30. Green DP, Morgan JP. Correlation between muscle morphology of the transverse carpal ligament and branching pattern of the motor branch of median nerve. J Hand Surg Am. 2008;33(9):1505-1511. doi: 10.1016/j.jhsa.2008.05.025.
Review
For citations:
Izmalkov S.N., Semenkin O.M., Bratiychuk A.N., Usov A.K., Demchenko N.A., Guseva А.E., Khairullina K.F. Results of a differentiated approach to open decompression of the median nerve in carpal tunnel syndrome. Genij Ortopedii. 2026;32(2):172-185. https://doi.org/10.18019/1028-4427-2026-32-2-172-185
JATS XML





























