The structural reorganization of the skeletal muscle being reinnervized for low-frequency electrical stimulation

Abstract

The histological, stereological and morphometric analysis of structural changes of the anterior tibial muscle subjected to reinnervation has been made experimentally in 7 dogs at an early stage of canine sciatic nerve posttraumatic regeneration under the influence of therapy using «Myoritm» device, which was performed within the period from 4 to 11 weeks after nerve cutting and primary suturing. It has been established that the vascularization of the muscle being reinnervized by the end of stimulation course exceeds not only the non-stimulated control, but even the value of intact muscle, creating the conditions for survival of muscle fibers in atrophic and normotrophic state, as well as for secondary myogenesis activation.