Modeling in vitro molecular reactions of blood mononuclear leukocytes to titanium implants with modified surface in patients with hereditary collagenopathies

Abstract

In vitro modeling of molecular reactions of peripheral blood mononuclear leukocytes to contact with implants which are perspective for improvement of osteosynthesis techniques can be used, in our opinion, for prognostic estimation of acceptance/rejection of artificial materials and the prospective usage for surgical treatment of patients with osteogenesis imperfecta and connective tissue dysplasia.