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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">genort</journal-id><journal-title-group><journal-title xml:lang="ru">Гений ортопедии</journal-title><trans-title-group xml:lang="en"><trans-title>Genij Ortopedii</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1028-4427</issn><issn pub-type="epub">2542-131X</issn><publisher><publisher-name>ЦЕНТР ИЛИЗАРОВА</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">genort-356</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original articles</subject></subj-group></article-categories><title-group><article-title>Радионуклидная оценка остеогенеза при замещении дефектов костей нижней конечности у больных с гигантоклеточной опухолью</article-title><trans-title-group xml:lang="en"><trans-title>RADIONUCLIDE EVALUATION OF DISTRACTIONAL OSTEOGENESIS IN THE PROCESS OF SUBSTITUTION OF LOWER LIMB BONE DEFECTS IN PATIENTS WITH GIANT-CELL</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куфтырев</surname><given-names>Л. М.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пожарищенский</surname><given-names>К. Э.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Носова</surname><given-names>Л. Н.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свешников</surname><given-names>А. А.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балаев</surname><given-names>И. И.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларионова</surname><given-names>Т. А.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Офицерова</surname><given-names>Н. В.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib></contrib-group><pub-date pub-type="collection"><year>1998</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>1998</year></pub-date><volume>0</volume><issue>1</issue><issue-title>№ 1 (1998)</issue-title><elocation-id>356</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Куфтырев Л., Пожарищенский К., Носова Л., Свешников А., Балаев И., Ларионова Т., Офицерова Н., 1998</copyright-statement><copyright-year>1998</copyright-year><copyright-holder xml:lang="ru">Куфтырев Л., Пожарищенский К., Носова Л., Свешников А., Балаев И., Ларионова Т., Офицерова Н.</copyright-holder><copyright-holder xml:lang="en">Куфтырев Л., Пожарищенский К., Носова Л., Свешников А., Балаев И., Ларионова Т., Офицерова Н.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ilizarov-journal.com/jour/article/view/356">https://www.ilizarov-journal.com/jour/article/view/356</self-uri><abstract><p>У 14 больных производили удаление гигантоклеточной опухоли, а дефект костной ткани замещали путем перемещения костных фрагментов. С помощью меченого технефора контролировали состояние костеобразования, изучали также концентрацию остеотропных гормонов и циклических нуклеотидов. Установили, что процесс регенерации у онкологических больных протекает медленее, чем у пациентов без  опухоли. У онкологических больных на этапах остеосинтеза больше паратирина. Существенно меньше концентрация кальцитонина и соматотропина. На основе изучения отношения цАМФ/цГМФ отмечено, что органотипическая перестройка дистракционного регенерата при замещении пострезекционных дефектов, по сравнению с посттравматическими, протекает более длительно.</p></abstract><trans-abstract xml:lang="en"><p>A giant-cell tumor was removed and a bone tissue defect was substituted by transportation of bone fragments in 14 patients. Osteogenesis status was controlled using labelled Technephor, and concentration of osteotropic hormones and cyclic nucleotides was studied as well. It was established, that the process of regeneration in oncological patients was lower, than in patients without tumors. Parathyrin amounts were more in oncological patients at osteosynthesis stages. Concentration of calcitonin and somatotropin was considerably less. On the basis of cAMP/cGMP ratio study it was noted, that organotypical reorganization of distraction regenerate was longer, when postresection defects were substituted in comparison with posttraumatic ones.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вывих надколенника</kwd><kwd>чрескостный остеосинтез</kwd><kwd>ранняя разработка коленного сустава</kwd><kwd>ультрасонография</kwd><kwd>компьютерная томография</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
