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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">genort</journal-id><journal-title-group><journal-title xml:lang="ru">Гений ортопедии</journal-title><trans-title-group xml:lang="en"><trans-title>Genij Ortopedii</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1028-4427</issn><issn pub-type="epub">2542-131X</issn><publisher><publisher-name>ЦЕНТР ИЛИЗАРОВА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18019/1028-4427-2025-31-1-66-73</article-id><article-id custom-type="elpub" pub-id-type="custom">genort-3165</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Случай из практики</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Case report</subject></subj-group></article-categories><title-group><article-title>Замещение тотального дефекта таранной кости  с использованием индивидуального 3D-имплантата из пористого титана  при нейроостеоартропатии Шарко у пациентки с нейросифилисом</article-title><trans-title-group xml:lang="en"><trans-title>Management of a total defect of the talus with a customized 3D-implant  made of porous titanium for Charcot neuroosteoarthropathy  in a patient with neurosyphilis: a case report</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4943-3440</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оснач</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Osnach</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Станислав Александрович Оснач — врач — травматолог-ортопед</p><p>Москва</p></bio><bio xml:lang="en"><p>Stanislav A. Osnach — orthopaedic surgeon</p><p>Moscow</p></bio><email xlink:type="simple">stas-osnach@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5077-2186</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Процко</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Protsko</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виктор Геннадьевич Процко — доктор медицинских наук, врач — травматолог-ортопед, руководитель Центра хирургии стопы и диабетической стопы</p><p>Москва</p></bio><bio xml:lang="en"><p>Victor G. Protsko — Doctor of Medical Sciences, orthopaedic surgeon, Head of the Center for Foot and Diabetic Foot Surgery</p><p>Moscow</p></bio><email xlink:type="simple">89035586679@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1276-5484</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оболенский</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Obolensky</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Николаевич Оболенский — кандидат медицинских наук, врач-хирург, врач — травматолог-ортопед, заведующий Центром гнойной хирургии</p><p>Москва</p></bio><bio xml:lang="en"><p>Vladimir N. Obolenskiy — Candidate of Medical Sciences, orthopaedic surgeon, Head of the Center for Purulent Surgery</p><p>Moscow</p></bio><email xlink:type="simple">gkb13@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазалов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazalov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Витальевич Мазалов — врач — травматолог-ортопед</p><p>Москва</p></bio><bio xml:lang="en"><p>Alexey V. Mazalov — orthopaedic surgeon</p><p>Moscow</p></bio><email xlink:type="simple">footdoctor@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5285-8303</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бреговский</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Bregovsky</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вадим Борисович Бреговский — доктор медицинских наук, врач-эндокринолог</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Vadim B. Bregovskiy — Doctor of Medical Sciences, endocrinologist</p><p>St. Petersburg</p></bio><email xlink:type="simple">dfoot.tdc@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6287-8132</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Василий Викторович Кузнецов — кандидат медицинских наук, врач — травматолог-ортопед</p><p>Москва</p></bio><bio xml:lang="en"><p>Vasiliy V. Kuznetsov — Candidate of Medical Sciences, orthopaedic surgeon</p><p>Moscow</p></bio><email xlink:type="simple">vkuznecovniito@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тамоев</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Tamoev</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саргон Константинович Тамоев — кандидат медицинских наук, врач — травматолог-ортопед, заведующий отделением</p><p>Москва</p></bio><bio xml:lang="en"><p>Sargon K. Tamoev — Candidate of Medical Sciences, orthopaedic surgeon, Head of the Department</p><p>Moscow</p></bio><email xlink:type="simple">sargonik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская клиническая больница им. С.С. Юдина</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yudin City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская клиническая больница им. С.С. Юдина; Российский университет дружбы народов имени Патриса Лумумбы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yudin City Clinical Hospital; Patrice Lumumba Peoples' Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Городская клиническая больница № 13 ДЗ г. Москвы; Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 13; Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Территориальный диабетологический центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SPb Territorial Diabetology Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>22</day><month>02</month><year>2025</year></pub-date><volume>31</volume><issue>1</issue><fpage>66</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Оснач С.А., Процко В.Г., Оболенский В.Н., Мазалов А.В., Бреговский В.Б., Кузнецов В.В., Тамоев С.К., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Оснач С.А., Процко В.Г., Оболенский В.Н., Мазалов А.В., Бреговский В.Б., Кузнецов В.В., Тамоев С.К.</copyright-holder><copyright-holder xml:lang="en">Osnach S.A., Protsko V.G., Obolensky V.N., Mazalov A.V., Bregovsky V.B., Kuznetsov V.V., Tamoev S.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ilizarov-journal.com/jour/article/view/3165">https://www.ilizarov-journal.com/jour/article/view/3165</self-uri><abstract><sec><title>Введение</title><p>Введение. Нейропатическая артропатия, или артропатия Шарко, характеризуется быстро прогрессирующей деструкцией костей на фоне нарушения ноцицептивной и проприоцептивной иннервации пораженной конечности. В последние годы появились публикации о применения 3D-моделирования и 3D-печати имплантатов из пористого титана для замещения крупных костных дефектов в области стопы, но нами найдено всего два описания клинических случаев применения 3D-имплантатов из пористого титана у пациентов с артропатией Шарко.</p><p>Цель работы — продемонстрировать и проанализировать результаты выполнения резекционного пяточно-большеберцового артродеза с пластикой дефекта индивидуальным 3D-имплантатом из пористого титана у пациентки с манифестацией артропатии Шарко как осложнения третичного сифилиса.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Женщина 50 лет, с сифилисом в анамнезе в течение 26 лет, через 2 мес. после выполнения тотального эндопротезирования левого коленного сустава отметила появление признаков воспаления в области голеностопного сустава во время увеличения нагрузки. По данным обследования выявлено тотальное разрушение таранной кости, установлен диагноз: нейроостеоартропатия Шарко стопы, активная стадия. Через 2,5 мес. разгрузки по результатам проведенного КТ-исследования левого голеностопного сустава выполнено 3D-моделирование и изготовлен индивидуальный 3D-имплантат из пористого титана. Пациентке произведен резекционный пяточно-большеберцовый артродез с забором аутотрансплантата из канала большеберцовой кости и пластикой дефекта 3D-имплантатом, осуществлена фиксация аппаратом Илизарова. Через 5 мес. после операции выполнен демонтаж аппарата Илизарова.</p></sec><sec><title>Результаты</title><p>Результаты. В отдаленном периоде наблюдений, по данным контрольных рентгенограмм, наступила консолидация.</p></sec><sec><title>Обсуждение</title><p>Обсуждение. Предлагаемый способ оперативного лечения при тотальном разрушении таранной кости и образующемся вследствие этого дефект-диастазе позволяет произвести реконструктивное вмешательство с одномоментной компенсацией укорочения, вне зависимости от формы и величины дефекта, избежать вторичного укорочения конечности с сохранением ее опороспособности, тем самым, предупреждая возникновение вторичных перегрузочных изменений в смежных суставах. Требуются дополнительные исследования для уточнения показаний к  применению данного метода и определения критериев отбора пациентов.</p></sec><sec><title>Заключение</title><p>Заключение. В клиническом наблюдении результаты применения метода резекционного пяточно-большеберцового артродеза с пластикой дефекта индивидуальным 3D-имплантатом из пористого титана представляются обнадеживающими.</p></sec></abstract><trans-abstract xml:lang="en"><p>Introduction Neuropathic arthropathy, or Charcot arthropathy, is characterized by rapid progressive bone destruction due to impaired nociceptive and proprioceptive innervation of the affected limb. In recent years, there have been publications on the use of 3D modeling and 3D printing of porous titanium implants for filling large bone defects in the foot, but we found only two descriptions of clinical cases of 3D porous titanium implants in patients with Charcot arthropathy.</p><p>The aim of the work is to demonstrate and analyze the results of performing resection calcaneotibial arthrodesis with  defect plasty using a customized 3D implant made of porous titanium in a patient with manifestation of Charcot arthropathy as a complication of tertiary syphilis.</p><p>Materials and methods A 50-year-old woman, with a history of syphilis for 26 years, noted the signs of inflammation in the ankle joint during increased loading two months after total knee arthroplasty on the left joint. The examination revealed total destruction of the talus. The diagnosis was Charcot neuroosteoarthropathy of the foot, active stage. After 2.5 months of unloading, based on the results of a CT study of the left ankle joint and 3D modeling, a 3D porous titanium customized implant was fabricated; resection calcaneotibial arthrodesis with autograft harvesting from the tibial canal and plastic surgery of the defect with a 3D implant and fixation with the Ilizarov apparatus were performed. Five months after the operation, consolidation was determined based on the results of control radiographs, and the Ilizarov apparatus was dismantled.</p><p>Discussion The proposed method of surgical treatment for total destruction of the talus and the resulting defect-diastasis allows for reconstructive intervention with immediate compensation of shortening, regardless of the shape and size of the defect, to avoid secondary shortening of the limb while maintaining its ability to support, thereby preventing the occurrence of secondary overload changes in the adjacent joints.</p><p>Conclusion The initial results in this clinical case seem encouraging, but additional research is required to clarify the indications and patient selection criteria for this treatment method.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артропатия Шарко</kwd><kwd>тотальный дефект таранной кости</kwd><kwd>индивидуальный  3D-пористый титановый имплантат</kwd><kwd>резекционный пяточно-большеберцовый артродез</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Charcot arthropathy</kwd><kwd>total defect of the talus</kwd><kwd>3D porous titanium customized implant</kwd><kwd>resection  calcaneotibial arthrodesis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Charcot JM. 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