genortГений ортопедииGenij Ortopedii1028-44272542-131XЦЕНТР ИЛИЗАРОВА10.18019/1028-4427-2021-27-2-220-226genort-2623Research ArticleОригинальные статьиOriginal articlesПрименение техники аутологичного индуцированного матрицей хондрогенеза в лечении пациентов с остеоартритом первого плюснефалангового суставаApplication of the technique of autologous matrix-induced chondrogenesis in the treatment of patients with osteoarthritis of the first metatarsophalangeal jointНурмухаметовМ. Р.NurmukhametovM. R.

Нурмухаметов Максим Ринатович,

г. Москва

Maxim R. Nurmukhametov, M.D.,

Moscow

nurmi91@mail.ruМакаровМ. А.MakarovM. A.

Макаров Максим Анатольевич, к. м. н.

г. Москва

Maxim A. Makarov, M.D., Ph.D.,

Moscow

ortopedniir@mail.ruБяликЕ. И.ByalikE. I.

Бялик Евгений Иосифович, д. м. н., профессор,

г. Москва

Evgeny I. Byalik, M.D., Ph.D., Professor,

Moscow

nervus11@yandex.ruХренниковЯ. Б.KhrennikovYa. B.

Хренников Ярослав Борисович, к. м. н.,

г. Москва

Yaroslav B. Khrennikov, M.D., Ph.D.,

Moscow

yaroslav79@yandex.ruБяликВ. Е.ByalikV. E.

Бялик Валерий Евгеньевич,

г. Москва

Valery E. Byalik, M.D.,

Moscow

nervus11@yandex.ruНестеренкоВ. А.NesterenkoV. A.

Нестеренко Вадим Андреевич,

г. Москва

Vadim A. Nesterenko, M.D.,

Moscow

swimguy91@mail.ruФедеральное государственное бюджетное научное учреждение «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologRussian FederationФедеральное государственное бюджетное учреждение «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА России»РоссияFederal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies FMBA of RussiaRussian Federation202128042021272№ 2 (2021)220226Copyright © Нурмухаметов М.Р., Макаров М.А., Бялик Е.И., Хренников Я.Б., Бялик В.Е., Нестеренко В.А., 20212021Нурмухаметов М.Р., Макаров М.А., Бялик Е.И., Хренников Я.Б., Бялик В.Е., Нестеренко В.А.Nurmukhametov M.R., Makarov M.A., Byalik E.I., Khrennikov Y.B., Byalik V.E., Nesterenko V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.ilizarov-journal.com/jour/article/view/2623Введение

Введение. На сегодняшний день не существует единого подхода к выбору тактики хирургического лечения остеоартрита первого плюснефалангового сустава (ОА I ПФС). С другой стороны, известно, что при наличии костно-хрящевых дефектов в тазобедренном, коленном и голеностопном суставах успешно применяется техника аутологичного индуцированного матрицей хондрогенеза. В связи с этим нами предложено применение данной техники в лечении пациентов с ОА I ПФС.

Цель

Цель. Изучить возможность хирургического лечения пациентов с ОА I ПФС с использованием хондропластики по технике аутологичного индуцированного матрицей хондрогенеза, продемонстрировать ближайшие и среднесрочные результаты выполненных операций.

Материалы и методы

Материалы и методы. К настоящему времени хондропластика выполнена 15 пациентам (16 стоп) с ОА I ПФС. При обследовании определялся объем движений в I ПФС; состояние оценивалось по таким шкалам как ВАШ боли, AOFAS, FFI. Хондропластика I ПФС осуществлялась по технике индуцированного хондрогенеза с использованием коллагеновой матрицы. Результаты операций оценивались через 3, 6 и 12 месяцев.

Результаты

Результаты. Уже через 3 месяца после операции отмечено выраженное значимое увеличение объема движений и уменьшение боли в I ПФС. Через 6 и 12 месяцев наблюдалась умеренная положительная динамика.

Заключение

Заключение. Результаты проведенных операций показали, что хондропластика I ПФС является эффективным методом хирургического лечения, позволяющим купировать боль и существенно улучшать качество жизни пациентов с ОА I ПФС. При этом необходимо изучение отдаленных результатов. 

Introduction

Introduction. To date, there is no unified approach to the choice of tactics in surgical treatment of osteoarthritis of the first metatarsophalangeal joint (OA of the first MTP joint). On the other hand, it is known that the technique of autologous matrix-induced chondrogenesis has been successfully used for osteochondral defects in the hip, knee and ankle joints. Therefore, we have proposed to use this technique in the treatment of patients with OA of the first MTP joint.

Purpose

Purpose. To study the possibility of surgical treatment of patients with OA of the first MTP joint with the use of chondroplasty utilizing the technique of autologous matrix-induced chondrogenesis, to demonstrate the immediate and mid-term results of such operations.

Materials and methods

Materials and methods. Chondroplasty was performed in 15 patients (16 feet) with OA of the first MTP joint. The examination determined the range of motion in of the first MTP joint; the condition was assessed according to such scales as VAS for pain, AOFAS, FFI. Chondroplasty in of the first MTP joint was performed with the technique of induced chondrogenesis using a collagen matrix. The results of the operations were evaluated after 3, 6 and 12 months.

Results

Results. As early as 3 months after the operation, there was a marked significant increase in the range of motion and a decrease in pain of the first MTP joint. Moderate positive dynamics were observed after 6 and 12 months.

Conclusion

Conclusion. The results of the operations showed that chondroplasty of the first MTP joint is an effective method of surgical treatment that provides pain relief and significantly improves the quality of life of patients with OA of the first MTP joint. However, it is necessary to study long-term results.

I плюснефаланговый суставостеоартритхондропластикахондрогенезколлагеновая матрицаfirst metatarsophalangeal jointosteoarthritischondroplastychondrogenesiscollagen matrixReferencesБережной С.Ю. Артроз первого плюснефалангового сустава: чрескожное оперативное лечение, выбор хирургической методики, клинико-рентгенологическая классификация // Травматология и ортопедия России. 2017. Т. 23, № 1. С. 8-22. DOI: 10.21823/2311-2905-2017-23-1-8-22Berezhnoi S.Iu. Artroz pervogo pliusnefalangovogo sustava: chreskozhnoe operativnoe lechenie, vybor khirurgicheskoi metodiki, kliniko-rentgenologicheskaia klassifikatsiia [Arthrosis of the first metatarsophalangeal joint: percutaneous surgical treatment, choice of surgical technique, clinical and roentgenological classification]. Travmatologiia i Ortopediia Rossii, 2017, vol. 23, no. 1, pp. 8-22. (in Russian) DOI: 10.21823/2311-2905-2017-23-1-8-22McNeil D.S., Baumhauer J.F., Glazebrook M.A. Evidence-based analysis of the efficacy for operative treatment of hallux rigidus // Foot Ankle Int. 2013. Vol. 34, No 1. P. 15-32. DOI: 10.1177/1071100712460220McNeil D.S., Baumhauer J.F., Glazebrook M.A. Evidence-based analysis of the efficacy for operative treatment of hallux rigidus. Foot Ankle Int., 2013, vol. 34, no. 1, pp. 15-32. DOI: 10.1177/1071100712460220Sorbie C., Saunders G.A. Hemiarthroplasty in the treatment of hallux rigidus // Foot Ankle Int. 2008. Vol. 29, No 3. P. 273-281. DOI: 10.3113/FAI.2008.0273Sorbie C., Saunders G.A. Hemiarthroplasty in the treatment of hallux rigidus. Foot Ankle Int., 2008, vol. 29, no. 3, pp. 273-281. DOI: 10.3113/FAI.2008.0273The modified oblique Keller capsular interpositional arthroplasty for hallux rigidus / R.B. Mackey, A.B. Thomson, O. Kwon, M.J. Mueller, J.E. Johnson // J. Bone Joint Surg. Am. 2010. Vol. 92, No 10. P. 1938-1946. DOI: 10.2106/JBJS.I.00412Mackey R.B., Thomson A.B., Kwon O., Mueller M.J., Johnson J.E. The modified oblique Keller capsular interpositional arthroplasty for hallux rigidus. J. Bone Joint Surg. Am., 2010, vol. 92, no. 10, pp. 1938-1946. DOI: 10.2106/JBJS.I.00412.Comparison of Arthrodesis, Resurfacing Hemiarthroplasty, and Total Joint Replacement in the Treatment of Advanced Hallux Rigidus / M. Erdil, N.M. Elmadag, G. Polat, N. Tunçer, K. Bilsel, V. Uçan, O.F. Erkoçak, C.Sen // J. Foot Ankle Surg. 2013. Vol. 52. P. 588-593. DOI: 10.1053/j.jfas.2013.03.014Erdil M., Elmadag N.M., Polat G., Tunçer N., Bilsel K., Uçan V., Erkoçak O.F., Sen C. Comparison of Arthrodesis, Resurfacing Hemiarthroplasty, and Total Joint Replacement in the Treatment of Advanced Hallux Rigidus. J. Foot Ankle Surg., 2013, vol. 52, pp. 588-593. DOI: 10.1053/j.jfas.2013.03.014The importance of the length of the first metatarsal and the proximal phalanx of hallux in the etiopathogeny of the hallux rigidus / A. Calvo, R. Viladot, J. Giné, F. Alvarez // Foot Ankle Surg. 2009. Vol. 15, No 2. P. 69-74. DOI: 10.1016/j.fas.2008.08.001Calvo A., Viladot R., Giné J., Alvarez F. The importance of the length of the first metatarsal and the proximal phalanx of hallux in the etiopathogeny of the hallux rigidus. Foot Ankle Surg., 2009, vol. 15, no. 2, pp. 69-74. DOI: 10.1016/j.fas.2008.08.001.Keiserman L., Sammarco J., Sammarco G.J. Surgical treatment ofthe hallux rigidus// FootAnkleClin. N.Am. 2005. Vol. 10. P. 75-96. DOI: 10.1016/j.fcl.2004.09.005Keiserman L., Sammarco J., Sammarco G.J. Surgical treatment of the hallux rigidus. Foot Ankle Clin. N. Am., 2005, vol. 10, pp. 75-96. DOI: 10.1016/j.fcl.2004.09.005Mid- and long-term results of the joint preserving therapy of hallux rigidus / H. Waizy, M.A. Czardybon, C. Stukenborg-Colsman, C. Wingenfeld, M. Wellmann, H. Windhagen, D. Frank // Arch. Orthop. Trauma Surg. 2010. Vol. 130, No 2. P. 165-170. DOI: 10.1007/s00402-009-0857-1Waizy H., Czardybon M.A., Stukenborg-Colsman C., Wingenfeld C., Wellmann M., Windhagen H., Frank D. Mid- and long-term results of the joint preserving therapy of hallux rigidus. Arch. Orthop. Trauma Surg., 2010, vol. 130, no. 2, pp. 165-170. DOI: 10.1007/s00402-009-0857-1Quantitative motion analysisin patients with hallux rigidus before and after cheilectomy / K. Canseco,J. Long, R. Marks, M.S. Khazzam, G. Harris // J. Orthop. Res. 2009. Vol. 27, No 1. P. 128-134. DOI: 10.1002/jor.20711Canseco K., Long J., Marks R., Khazzam M.S., Harris G. Quantitative motion analysis in patients with hallux rigidus before and after cheilectomy. J. Orthop. Res., 2009, vol. 27, no. 1, pp. 128-134. DOI: 10.1002/jor.20711Seibert N.R., Kadakia A.R. Surgical management of hallux rigidus: cheilectomy and osteotomy (phalanx and metatarsal) // Foot Ankle Clin. 2009. Vol. 14, No 1. P. 9-22. DOI: 10.1016/j.fcl.2008.11.002Seibert N.R., Kadakia A.R. Surgical management of hallux rigidus: cheilectomy and osteotomy (phalanx and metatarsal). Foot Ankle Clin., 2009, vol. 14, no. 1, pp. 9-22. DOI: 10.1016/j.fcl.2008.11.002Prospective Assessment of Dorsal Cheilectomy for Hallux Rigidus Using a Patient-reported Outcome Score / T. Harrison, E. Fawzy, F. Dinah, S.H. Palmer // J. Foot Ankle Surg. 2010. Vol. 49, No 3. P. 232-237. DOI: 10.1053/j.jfas.2010.02.004Harrison T., Fawzy E., Dinah F., Palmer S.H. Prospective Assessment of Dorsal Cheilectomy for Hallux Rigidus Using a Patient-reported Outcome Score. J. Foot Ankle Surg., 2010, vol. 49, no. 3, pp. 232-237. DOI: 10.1053/j.jfas.2010.02.004Coughlin M.J., Shurnas P.S. Hallux rigidus. Grading and long-term results of operative treatment // J. Bone Joint Surg. Am. 2003. Vol. 85, No 11. P. 2072-2088. DOI: 10.2106/00004623-200311000-00003Coughlin M.J., Shurnas P.S. Hallux rigidus. Grading and long-term results of operative treatment. J. Bone Joint Surg. Am., 2003, vol. 85, no. 11, pp. 2072-2088. DOI: 10.2106/00004623-200311000-00003Peace R.A., Hamilton G.A. End-Stage Hallux Rigidus // Clin. Podiatr. Med. Surg. 2012. Vol. 29, No 3. P. 341-353. DOI: 10.1016/j.cpm.2012.04.002Peace R.A., Hamilton G.A. End-Stage Hallux Rigidus. Clin. Podiatr. Med. Surg., 2012, vol. 29, no. 3, pp. 341-353. DOI: 10.1016/j.cpm.2012.04.002End-stage osteoarthritis of the great toe/hallux rigidus: a review of the alternatives to arthrodesis: implant versus osteotomies and arthroplasty techniques / A.D. Perler, V. Nwosu, D. Christie, K. Higgins // Clin. Podiatr. Med. Surg. 2013. Vol. 30, No 3. P. 351-395, DOI: 10.1016/j.cpm.2013.04.011Perler A.D., Nwosu V., Christie D., Higgins K. End-stage osteoarthritis of the great toe/hallux rigidus: a review of the alternatives to arthrodesis: implant versus osteotomies and arthroplasty techniques. Clin. Podiatr. Med. Surg., 2013, vol. 30, no. 3, pp. 351-395, DOI: 10.1016/j.cpm.2013.04.011Benthien J.P., Behrens P. Autologous matrix-induced chondrogenesis (AMIC): combining microfracturing and a collagen I/III matrix for articular cartilage resurfacing // Cartilage. 2010. Vol. 1, No 1. P. 65-68. DOI: 10.1177/1947603509360044Benthien J.P., Behrens P. Autologous matrix-induced chondrogenesis (AMIC): combining microfracturing and a collagen I/III matrix for articular cartilage resurfacing. Cartilage, 2010, vol. 1, no. 1, pp. 65-68. DOI: 10.1177/1947603509360044Outcome of Autologous Matrix Induced Chondrogenesis (AMIC) in cartilage knee surgery: data of the AMIC Registry / J. Gille, P. Behrens, P. Volpi, L. de Girolamo, E. Reiss, W. Zoch, S. Anders // Arch. Orthop. Trauma Surg. 2013. Vol. 133, No 1. P. 87-93. DOI: 10.1007/s00402-012-1621-5Gille J., Behrens P., Volpi P., De Girolamo L., Reiss E., Zoch W., Anders S. Outcome of Autologous Matrix Induced Chondrogenesis (AMIC) in cartilage knee surgery: data of the AMIC Registry. Arch. Orthop. Trauma Surg., 2013, vol. 133, no. 1, pp. 87-93. DOI: 10.1007/s00402-012-1621-5Jannelli E., FontanaA.Arthroscopic treatment of chondral defects in the hip:AMIC, MACI, microfragmented adipose tissue transplantation (MATT) and other options // SICOT J. 2017. Vol. 3. P. 43. DOI: 10.1051/sicotj/2017029Jannelli E., Fontana A. Arthroscopic treatment of chondral defects in the hip: AMIC, MACI, microfragmented adipose tissue transplantation (MATT) and other options. SICOT J., 2017, vol. 3, pp. 43. DOI: 10.1051/sicotj/2017029All-arthroscopic AMIC® (AT-AMIC®) technique with autologous bone graft for talar osteochondral defects: clinical and radiological results / F.G. Usuelli, R. D’Ambrosi, C. Maccario, M. Boga, L. de Girolamo // Knee Surg. Sports Traumatol. Arthrosc. 2018. Vol. 26, No 3. P. 875-881. DOI: 10.1007/s00167-016-4318-4Usuelli F.G., D’Ambrosi R., Maccario C., Boga M., De Girolamo L. All-arthroscopic AMIC® (AT-AMIC®) technique with autologous bone graft for talar osteochondral defects: clinical and radiological results. Knee Surg. Sports Traumatol. Arthrosc., 2018, vol. 26, no. 3, pp. 875-881. DOI: 10.1007/s00167-016-4318-4Fontana A., De Girolamo L. Sustained five-year benefit of autologous matrix-induced chondrogenesis for femoral acetabular impingement-induced chondral lesions compared with microfracture treatment // Bone Joint J. 2015. Vol. 97-B, No 5. P. 628-635. DOI: 10.1302/0301-620X.97B5.35076Fontana A., De Girolamo L. Sustained five-year benefit of autologous matrix-induced chondrogenesis for femoral acetabular impingement-induced chondral lesions compared with microfracture treatment. Bone Joint J., 2015, vol. 97-B, no. 5, pp. 628-635. DOI: 10.1302/0301-620X.97B5.35076Использование хондропластики I плюснефалангового сустава по технике аутологичного индуцированного матрицей хондрогенеза для лечения пациентов с hallux rigidus: ближайшие результаты / М.Р. Нурмухаметов, М.А. Макаров, Е.И. Бялик, В.Е. Бялик, В.А. Нестеренко // Научно-практическая ревматология. 2020. Т. 58, № 1. С. 97-101. DOI: 10.14412/1995-4484-2020-97-101Nurmukhametov M.R., Makarov M.A., Bialik E.I., Bialik V.E., Nesterenko V.A. Ispolzovanie khondroplastiki i pliusnefalangovogo sustava po tekhnike autologichnogo indutsirovannogo matritsei khondrogeneza dlia lecheniia patsientov s hallux rigidus: blizhaishie rezultaty [The use of chondroplasty of the first metatarsophalangeal joint according to the technique of autologous matrix-induced chondrogenesis for the treatment of patients with hallux rigidus: short-term results]. Nauchno-Prakticheskaia Revmatologiia, 2020, vol. 58, no. 1, pp. 97-101. (in Russian) DOI: 10.14412/1995-4484-2020-97-101Хондропластика по технике аутологичного индуцированного матрицей хондрогенеза (AMIC) как новый метод хирургического лечении пациентов с hallux rigidus. Ближайшие и среднесрочные результаты / М.Р. Нурмухаметов, М.А. Макаров, С.А. Макаров, Е.И. Бялик, Я.Б. Хренников, В.Е. Бялик, В.А. Нестеренко // III Международный конгресс ассоциации ревмоортопедов: тез. докл. Воронеж: Научная книга, 2019. С. 85-87.Nurmukhametov M.R., Makarov M.A., Makarov S.A., Bialik E.I., Khrennikov Ia.B., Bialik V.E., Nesterenko V.A. Khondroplastika po tekhnike autologichnogo indutsirovannogo matritsei khondrogeneza (AMIC) kak novyi metod khirurgicheskogo lecheniia patsientov s hallux rigidus. Blizhaishie i srednesrochnye rezultaty [Chondroplasty according to the technique of autologous matrix-induced chondrogenesis (AMIC) as a new method of surgical treatment of patients with hallux rigidus. Short-term and med-term results]. III Mezhdunarodnyi Kongress Assotsiatsii Revmoortopedov: tez. dokl. [Proceedings of the III International Congress of the Association of Rheumoorthopedists]. Voronezh, Nauchnaia Kniga, 2019, pp. 85-87. (in Russian)Clinical rating systemsfor the ankle-hindfoot, midfoot, hallux and lesser toes/ H.B. Kitaoka, I.J.Alexander, R.S.Adelaar,J.A. Nunley, M.S. Myerson, M. Sanders // Foot Ankle Int. 1994. Vol. 15, No 7. P. 349-353. DOI: 10.1177/107110079401500701Kitaoka H.B., Alexander I.J., Adelaar R.S., Nunley J.A., Myerson M.S., Sanders M. Clinical rating systems for the ankle-hindfoot, midfoot, hallux and lesser toes. Foot Ankle Int., 1994, vol. 15, no. 7, pp. 349-353. DOI: 10.1177/107110079401500701Budiman-Mak E., Conrad K.J., Roach K.E. The Foot Function Index: a measure of foot pain and disability // J. Clin. Epidemiol. 1991. Vol. 44, No 6. P. 561-570. DOI: 10.1016/0895-4356(91)90220-4Budiman-Mak E., Conrad K.J., Roach K.E. The Foot Function Index: a measure of foot pain and disability. J. Clin. Epidemiol., 1991, vol. 44, no. 6, pp. 561-570. DOI: 10.1016/0895-4356(91)90220-4Pratt J. Remarks on Zeros and Ties in the Wilcoxon Signed Rank Procedures // Journal of the American Statistical Association. 1959. Vol. 54, No 287. P. 655-667. DOI: 10.2307/2282543Pratt J. Remarks on Zeros and Ties in the Wilcoxon Signed Rank Procedures. Journal of the American Statistical Association, 1959, vol. 54, no. 287, pp. 655-667. DOI: 10.2307/2282543Сидоренко Е.В. Методы математической обработки в психологии. СПб.: Речь, 2000. 350 с.Sidorenko E.V. Metody matematicheskoi obrabotki v psikhologii [Methods of mathematical processing in psychology]. SPb., Rech, 2000, 350 p. (in Russian)A plantar-flexor-shortening osteotomy for hallux rigidus: a retrospective analysis / R. Derner, K. Goss, H.N. Postowski, N. Parsley // J. Foot Ankle Surg. 2005. Vol. 44, No 5. P. 377-389. DOI: 10.1053/j.jfas.2005.07.010Derner R., Goss K., Postowski H.N., Parsley N. A plantar-flexor-shortening osteotomy for hallux rigidus: a retrospective analysis. J. Foot Ankle Surg., 2005, vol. 44, no. 5, pp. 377-389. DOI: 10.1053/j.jfas.2005.07.010Freeman B.L., Hardy M.A. Multiplanar phalangeal and metatarsal osteotomies for hallux rigidus // Clin. Podiatr. Med. Surg. 2011. Vol. 28, No 2. P. 329-344. DOI: 10.1016/j.cpm.2011.03.002Freeman B.L., Hardy M.A. Multiplanar phalangeal and metatarsal osteotomies for hallux rigidus. Clin. Podiatr. Med. Surg., 2011, vol. 28, no. 2, pp. 329-344. DOI: 10.1016/j.cpm.2011.03.002Goucher N.R., Coughlin M.J. Hallux metatarsophalangeal joint arthrodesis using dome-shaped reamers and dorsal plate fixation: a prospective study // Foot Ankle Int. 2006. Vol. 27, No 11. P. 869-876. DOI: 10.1177/107110070602701101Goucher N.R., Coughlin M.J. Hallux metatarsophalangeal joint arthrodesis using dome-shaped reamers and dorsal plate fixation: a prospective study. Foot Ankle Int., 2006, vol. 27, no. 11, pp. 869-876. DOI: 10.1177/107110070602701101Bennett G.L., Sabetta J. First metatarsal phalangeal joint arthrodesis: evaluation of plate and screw fixation // Foot Ankle Int. 2009. Vol. 30, No 8. P. 752-757. DOI: 10.3113/FAI.2009.0752Bennett G.L., Sabetta J. First metatarsal phalangeal joint arthrodesis: evaluation of plate and screw fixation. Foot Ankle Int., 2009, vol. 30, no. 8, pp. 752-757. DOI: 10.3113/FAI.2009.0752Review of 107 hallux MTP joint arthrodesis using dome-shaped reamers and a stainless-steel dorsal plate / J.K. Ellington, C.P. Jones, B.E. Cohen, W.H. Davis, F. Nickisch, R.B. Anderson // Foot Ankle Int. 2010. Vol. 31, No 5. P. 385-390. DOI: 10.3113/FAI.2010.0385Ellington J.K., Jones C.P., Cohen B.E., Davis W.H., Nickisch F., Anderson R.B. Review of 107 hallux MTP joint arthrodesis using dome-shaped reamers and a stainless-steel dorsal plate. Foot Ankle Int., 2010, vol. 31, no. 5, pp. 385-390. DOI: 10.3113/FAI.2010.0385Хирургическое лечение перегрузочной метатарзалгии / Д.С. Бобров, Л.Ю. Слиняков, А.Г. Сухарева, М.Ю. Холодаев, Л.А. Якимов // Московский хирургический журнал. 2014. № 3 (37). С. 25-27.Bobrov D.S., Sliniakov L.Iu., Sukhareva A.G., Kholodaev M.Iu., Iakimov L.A. Khirurgicheskoe lechenie peregruzochnoi metatarzalgii [Surgical treatment of overload metatarsalgia]. Moskovskii Khirurgicheskii Zhurnal, 2014, no. 3 (37), pp. 25-27. (in Russian)Foot function after fusion of the first metatarsophalangeal joint / D.J. van Doeselaar, P.J. Heesterbeek, J.W. Louwerens, B.A. Swierstra // Foot Ankle Int. 2010. Vol. 31, No 8. P. 670-675. DOI: 10.3113/FAI.2010.0670Van Doeselaar D.J., Heesterbeek P.J., Louwerens J.W., Swierstra B.A. Foot function after fusion of the first metatarsophalangeal joint. Foot Ankle Int., 2010, vol. 31, no. 8, pp. 670-675. DOI: 10.3113/FAI.2010.0670First metatarsophalangeal arthrodesis: a clinical, pedobarographic and gait analysis study / P.F. DeFrino, J.W. Brodsky, F.E. Pollo, S.J. Crenshaw, A.D. Beischer // Foot Ankle Int. 2002. Vol. 23, No 6. P. 496-502. DOI: 10.1177/107110070202300605DeFrino P.F., Brodsky J.W., Pollo F.E., Crenshaw S.J., Beischer A.D. First metatarsophalangeal arthrodesis: a clinical, pedobarographic and gait analysis study. Foot Ankle Int., 2002, vol. 23, no. 6, pp. 496-502. DOI: 10.1177/107110070202300605.Hallux rigidus: joint preserving alternatives to arthrodesis – a review of the literature / H. Polzer, S. Polzer, M. Brumann, W. Mutschler, M. Regauer // World J. Orthop. 2014. Vol. 5, No 1. P. 6-13. DOI: 10.5312/wjo.v5.i1.6Polzer H., Polzer S., Brumann M., Mutschler W., Regauer M. Hallux rigidus: joint preserving alternatives to arthrodesis – a review of the literature. World J. Orthop., 2014, vol. 5, no. 1, pp. 6-13. DOI: 10.5312/wjo.v5.i1.6Richter M., Zech S., Andreas Meissner S. Matrix-associated stem cell transplantation (MAST) in chondral defects of the 1st metatarsophalangeal joint is safe and effective – 2-year-follow-up in 20 patients // Foot Ankle Surg. 2017. Vol. 23, No 3. P. 195-200. DOI: 10.1016/j.fas.2016.05.318Richter M., Zech S., Andreas Meissner S. Matrix-associated stem cell transplantation (MAST) in chondral defects of the 1st metatarsophalangeal joint is safe and effective – 2-year-follow-up in 20 patients. Foot Ankle Surg., 2017, vol. 23, no. 3, pp. 195-200. DOI: 10.1016/j.fas.2016.05.318

The authors declare that there are no conflicts of interest present.