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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">genort</journal-id><journal-title-group><journal-title xml:lang="ru">Гений ортопедии</journal-title><trans-title-group xml:lang="en"><trans-title>Genij Ortopedii</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1028-4427</issn><issn pub-type="epub">2542-131X</issn><publisher><publisher-name>ЦЕНТР ИЛИЗАРОВА</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">genort-1879</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Материалы съезда ортопедов-травматологов Уральского федерального округа</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Materials of a congress of orthopedists-traumatologists of the Ural Federal District</subject></subj-group></article-categories><title-group><article-title>Возрастные особенности гемокоагуляционных изменений при эндопротезировании тазобедренного или коленного сустава</article-title><trans-title-group xml:lang="en"><trans-title>Age-related special features of hemocoagulation changes for the hip or knee arthroplasty</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антропова</surname><given-names>И. П.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юшков</surname><given-names>Б. Г.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рейно</surname><given-names>Е. В.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib></contrib-group><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2012</year></pub-date><volume>0</volume><issue>3</issue><issue-title>№ 3 (2012)</issue-title><elocation-id>1879</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Антропова И., Юшков Б., Рейно Е., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Антропова И., Юшков Б., Рейно Е.</copyright-holder><copyright-holder xml:lang="en">Антропова И., Юшков Б., Рейно Е.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ilizarov-journal.com/jour/article/view/1879">https://www.ilizarov-journal.com/jour/article/view/1879</self-uri><abstract><p>Целью исследования стало изучение влияния возраста на характер изменений в системе гемостаза у 77 пациентов в динамике после эндопротезирования крупных суставов. Определяли показатели свертывания, фибринолиза, антикоагулянты. В послеоперационном периоде у пожилых пациентов по сравнению с пациентами среднего возраста выявлено более медленное восстановление уровня факторов протромбинового комплекса, менее выраженный реактивный тромбоцитоз, более высокая активность формирования и лизиса фибрина, большая активность ингибитора активатора плазминогена I типа, отражающая эндотелиальную дисфункцию. Выводы. Более интенсивное формирование фибрина и более выраженное
повреждение эндотелия у пожилых пациентов по сравнению с пациентами среднего возраста могут усиливать риск развития послеоперационного тромбоза глубоких вен.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to investigate the influence of age on the character of changes in the hemostasis system dynamically in 77 patients underwent the large joint arthroplasty. The parameters of coagulation, fibrinolysis were analyzed, as well as anticoagulants. Slower recovery of the level of prothrombin complex factors has been revealed, as well as less marked reactive thrombocytosis, higher activity of fibrin formation and lysis, greater activity of PAI-I reflecting endothelial dysfunction in the postoperative period in elderly patients in comparison with middle-age patients. Conclusions. More intensive fibrin formation and more pronounced endothelium damage in elderly patients may increase the risk of postoperative deep-vein thrombosis in comparison with middle-age patients.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
