Проведены клинико-генеалогические исследования болезни Шейерманна (БШ) и идиопатического сколиоза (ИС) в сравнительном аспекте в 35 семьях пробандов с БШ (532 человека). Клинико-рентгенологически обследовано 35 пробандов с БШ в возрасте от 14 до 19 лет и 212 членов их семей I-III степени родства в возрасте от 14 до 65 лет. При клинико-генеалогическом и клинико-рентгенологическом исследовании родственников пробандов были выявлены 124 (58,5%) пациента как с БШ, так и ИС, из них БШ у 84 (67,7%), ИС – у 40 (32,3%). БШ страдали преимущественно лица мужского пола, ИС женского пола. Результаты проведенного исследования показали смешанное наследование БШ и ИС в отдельно взятой семье.
Clinical-and-genealogical studies of Scheuermann disease (SD) and idiopathic scoliosis (IS) have been performed comparatively in 35 families of probands with SD (532 subjects). 35 probands with SD at the age of 14-19 years have been subjected to clinical-and-roentgenological examination/ as well as 212 members of their families of 1st-3th relation degree at the age of 14-65 years. The clinical-and-genealogical and clinical-and-roentgenological examinations of proband relatives have revealed 124 (58,5%) patients with both SD and IS, among them 84 (67,7%) patients suffered from SD and 40 (32,3%) – from IS. As it turned out, SD was observed mainly in male subjects and idiopathic scoliosis – mainly in female ones. The results of the study made demonstrated mixed inheritance of SD and IS in a separate family.
The authors declare that there are no conflicts of interest present.