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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">genort</journal-id><journal-title-group><journal-title xml:lang="ru">Гений ортопедии</journal-title><trans-title-group xml:lang="en"><trans-title>Genij Ortopedii</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1028-4427</issn><issn pub-type="epub">2542-131X</issn><publisher><publisher-name>ЦЕНТР ИЛИЗАРОВА</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">genort-1520</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original articles</subject></subj-group></article-categories><title-group><article-title>Биохимия протеогликанов синовиальной жидкости в динамике развития остеоартроза</article-title><trans-title-group xml:lang="en"><trans-title>Biochemistry of synovia proteoglycans in the dynamics of osteoarthrosis development</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Русова</surname><given-names>Т. В.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баитов</surname><given-names>В. С.</given-names></name></name-alternatives><email xlink:type="simple"></email></contrib></contrib-group><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2009</year></pub-date><volume>0</volume><issue>3</issue><issue-title>№ 3 (2009)</issue-title><elocation-id>1520</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Русова Т., Баитов В., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Русова Т., Баитов В.</copyright-holder><copyright-holder xml:lang="en">Русова Т., Баитов В.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.ilizarov-journal.com/jour/article/view/1520">https://www.ilizarov-journal.com/jour/article/view/1520</self-uri><abstract><p>В синовиальной жидкости больных остеартрозом разной стадии аналитически определяли содержание гликозаминогликанов (ГАГ) и комплексы протеогликанов (ПГ) методом электрофореза в геле агарозы. На ранних стадиях заболевания количество ГАГ в синовиальной жидкости возрастает, а на поздних – снижается, что отражает динамику изменений в суставном хряще. Количество ГАГ, их качественный состав и структурная агрегированность ПГ может служить диагностическим тестом риска возникновения и динамики развития остеоартроза.</p></abstract><trans-abstract xml:lang="en"><p>The content of glycosaminoglycans (GAG) and the complexes of proteoglycans (PG) were determined analytically in synovia of patients with osteoarthrosis of different stages by the method of electrophoresis in agarose gel. The amount of GAG in synovia increases at early stages of the disease, and at the late ones it decreases, thereby reflecting the dynamics of changes in articulate cartilage. The amount of GAG, their qualitative composition and PG structural aggregatbility can serve as a diagnostic test for risk of osteoarthrosis occurrence and its development dynamics.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
